Xeomin® 100 Units is a highly purified form of botulinum toxin type A, designed to treat various neuromuscular conditions and aesthetic concerns. Unlike other botulinum toxin products, Xeomin® is free from complexing proteins, which may reduce the risk of antibody development and potential resistance over time.
Key Features:
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Purity: Xeomin® contains only the active neurotoxin component, eliminating unnecessary proteins.
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Efficacy: Clinically proven to provide effective results in both therapeutic and aesthetic applications.
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Stability: Demonstrates stability at room temperature, facilitating storage and handling.
Benefits:
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Therapeutic Applications:
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Upper Limb Spasticity: Alleviates muscle stiffness in adults, enhancing mobility and quality of life.
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Cervical Dystonia: Reduces abnormal head positioning and neck pain associated with this condition.
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Blepharospasm: Mitigates involuntary eyelid twitching, improving visual function.
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Chronic Sialorrhea: Decreases excessive salivation in adults, addressing social and hygiene concerns.
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Aesthetic Applications:
- Glabellar Lines: Smooths moderate to severe frown lines between the eyebrows, resulting in a more youthful appearance.
Usage Instructions:
Xeomin® is intended for intramuscular or intraglandular injection and should only be administered by qualified healthcare professionals experienced in the use of botulinum toxin products.
Dosage Recommendations:
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Chronic Sialorrhea in Adults:
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Inject into the parotid and submandibular glands bilaterally (four injection sites per session).
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Total recommended dose: 100 Units per session, divided in a 3:2 ratio between the parotid and submandibular glands.
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Repeat treatments should be based on clinical need, with intervals of no less than 16 weeks.
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Upper Limb Spasticity in Adults:
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Dosage varies based on muscle size, number, and location, as well as the severity of spasticity.
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Maximum total dose: Up to 400 Units per session.
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Repeat treatments should not occur more frequently than every 12 weeks.
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Cervical Dystonia:
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Initial recommended dose: 120 Units per session, adjusted based on individual response.
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Administered into affected neck muscles.
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Repeat treatments should be based on clinical need, with intervals of no less than 12 weeks.
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Blepharospasm:
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Initial dosing should consider previous treatments with botulinum toxin.
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If no prior treatment, a starting dose of 1.25 to 2.5 Units per injection site is recommended.
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Administered into the orbicularis oculi muscle.
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Repeat treatments should not occur more frequently than every 12 weeks.
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Glabellar Lines:
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Total recommended dose: 20 Units per session.
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Divide into five equal intramuscular injections of 4 Units each: two in each corrugator muscle and one in the procerus muscle.
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Minimum interval between treatments: 3 months.
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Safety Considerations:
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Contraindications:
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Hypersensitivity to botulinum toxin type A or any excipients in the formulation.
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Presence of infection at the proposed injection sites.
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Warnings and Precautions:
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Potential for distant spread of toxin effect, leading to symptoms such as muscle weakness, dysphagia, or respiratory difficulties.
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Use with caution in patients with pre-existing neuromuscular disorders.
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Immediate medical attention is required if serious hypersensitivity reactions occur.
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Adverse Reactions:
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Common side effects include localized pain at the injection site, headache, and muscle weakness.
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Serious adverse events, though rare, may include dysphagia, respiratory difficulties, and allergic reactions.
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Drug Interactions:
- Caution is advised when used concomitantly with aminoglycosides or other agents that may potentiate the effect of botulinum toxin.
Storage and Handling:
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Store unopened vials in a refrigerator at 2°C to 8°C.
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Reconstituted solution should be used within 24 hours and stored under refrigeration.
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Do not freeze reconstituted solution.
All Celmade shipments originate from South Korea. We help the main features of sending products to more than 50 countries all around the world.
We will help you best delivery method after confirming the order. Shipping cost and delivery time vary depending on the destination
country, but it takes approximately 3-10 business days. This is based on
International Courier, DHL, FEDEX, Professional Courier (Russia region), etc.,
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and may change depending on the logistics situation in the destination country. This does not include Force Majeure, such as natural disasters, political circumstances, or delays in customs clearance.
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A Tracking Number is created to track the product and you can track the shipment.
If delivery is delayed by more than 10 days, please contact the Customs of your Country or the Customer Service Center of your Local Logistics Company directly. Delivery delays may be due to issues with Documents and Qualifications required for Customs Clearance and Taxation according to the Destination Country’s Tax Laws, and Celmade is not involved in taxes and customs clearance in the destination country.
For further inquiries, please contact the Celmade Customer Service Center.
